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MRS4853

Chemical Structure : MRS4853

CAS No.: 2839477-13-1

MRS4853

Catalog No.: PC-49620Not For Human Use, Lab Use Only.

MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MRS4853 is a selective P2Y6 receptor (P2Y6R) antagonist with IC50 of 0.46 uM (hP2Y6R), displays weak affinity for mP2Y6R (IC50=6.15 uM).

Physicochemical Properties

M.Wt 383.44
Formula C18H20F3NO3Si
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

triethyl((3-nitro-2-(trifluoromethyl)-2H-chromen-8-yl)ethynyl)silane

References

1. Jung YH, et al. Bioorg Med Chem Lett. 2022 Nov 1;75:128981.

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