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MRS7469

Chemical Structure : MRS7469

CAS No.: 2257428-60-5

MRS7469 (MRS 7469)

Catalog No.: PC-21511Not For Human Use, Lab Use Only.

MRS7469 is a potent and selective orthosteric A1 adenosine receptor (A1AR) agonist with Ki of 2.14 nM, >2000-fold selective for A1AR over other adenosine receptors.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MRS7469 is a potent and selective orthosteric A1 adenosine receptor (A1AR) agonist with Ki of 2.14 nM, >2000-fold selective for A1AR over other adenosine receptors.

Physicochemical Properties

M.Wt 389.46
Formula C19H27N5O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

(2R,3R,4S,5R)-2-(6-((dicyclobutylmethyl)-amino)-9H-purin-9-yl)-5-(hydroxymethyl)tetrahydrofuran-3,4-diol

References

1. Dilip K Tosh, et al. J Med Chem. 2019 Feb 14;62(3):1502-1522.

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