MSA-2 dimer | STING agonist | Probechem Biochemicals

Chemical Structure : MSA-2 dimer

MSA-2 dimer (diMSA-2)

Catalog No.: PC-26989Not For Human Use, Lab Use Only.

MSA-2 dimer (diMSA-2) is a selective, orally active non-nucleotide STING agonist with KD of 145 uM, binds to STING as a non-covalent dimer and exhibits long-term antitumor and immunogenic activity.

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Biological Activity

MSA-2 dimer (diMSA-2) is a selective, orally active non-nucleotide STING agonist with KD of 145 uM, binds to STING as a non-covalent dimer and exhibits long-term antitumor and immunogenic activity.

Physicochemical Properties

M.Wt	568.66
Formula	C29H28O8S2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	4,4'-(Propane-1,3-diylbis(6-methoxybenzo[b]thiophene-5,2-diyl))bis(4-oxobutanoic acid)

References

1. Pan BS, et al. An orally available non-nucleotide STING agonist with antitumor activity. Science. 2020;369(6506):eaba6098.

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MSA-2 dimer (diMSA-2)

Biological Activity

Physicochemical Properties

References

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