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Chemical Structure : MTEP hydrochloride
CAS No.: 1186195-60-7
Catalog No.: PC-43392Not For Human Use, Lab Use Only.
MTEP hydrochloride is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 25 mg | $108 | In stock | |
| 100 mg | $228 | In stock | |
| 500 mg | $358 | In stock | |
| 1 g | Get quote |
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MTEP hydrochloride is a potent, selective, non-competitive mGlu5 antagonist with IC50 of 5 nM and Ki of 16 nM; produces antidepressant effects in several rodent models of depression, also demonstrates neuroprotective potential by preventing excitotoxic neuronal damage.
| M.Wt | 236.7206 | |
| Formula | C11H9ClN2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Pyridine, 3-[2-(2-methyl-4-thiazolyl)ethynyl]-, hydrochloride (1:1) |
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1. Busse CS, et al. Neuropsychopharmacology. 2004 Nov;29(11):1971-9.
2. Keck TM, et al. ACS Med Chem Lett. 2012 Jul 12;3(7):544-549.
3. Rasmussen K, et al. Neuropharmacology. 2005 Feb;48(2):173-80.
4. Ossowska K, et al. Neuropharmacology. 2005 Sep;49(4):447-55.
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