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Chemical Structure : MTX-211
CAS No.: 1952236-05-3
Catalog No.: PC-70200Not For Human Use, Lab Use Only.
MTX-211 is a first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with IC50 of <100 nM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $158 | In stock | |
| 10 mg | $258 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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MTX-211 is a first-in-class, highly selective, dual inhibitor of PI3K and EGFR kinases with IC50 of <100 nM.
MTX-211 demonstrated in vivo anticancer activity against multiple KRAS mutant colorectal tumors.
MTX-211 shows limited off-target toxicity and a broad therapeutic window.
| M.Wt | 478.323 | |
| Formula | C20H14Cl2FN5O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Methanesulfonamide, N-[2-chloro-5-[4-[(3-chloro-4-fluorophenyl)amino]-6-quinazolinyl]-3-pyridinyl]- |
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