Chemical Structure : MW-150
Catalog No.: PC-60434Not For Human Use, Lab Use Only.
MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
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MW-150 (MW01-18-150 SRM) is a novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM; effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models; also can selectively modulate neuroinflammatory responses associated with pathology progression.
M.Wt | 381.483 | |
Formula | C24H23N5 | |
Appearance | Solid | |
Storage |
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Solubility |
10 mM in DMSO |
1. Roy SM, et al. ACS Chem Neurosci. 2015 Apr 15;6(4):666-80.
2. Zhou Z, et al. J Neuroinflammation. 2017 Apr 5;14(1):75.
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