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Chemical Structure : MW-150 hydrochloride
Catalog No.: PC-60432Not For Human Use, Lab Use Only.
A novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM.
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A novel potent, selective, CNS penetrant and orally active inhibitor of p38α MAPK with Ki of 101 nM; effectively suppresses hippocampal-dependent associative and spatial memory deficits in synaptic dysfunction mouse models; also can selectively modulate neuroinflammatory responses associated with pathology progression.
| M.Wt | 417.94 | |
| Formula | C24H24ClN5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Roy SM, et al. ACS Chem Neurosci. 2015 Apr 15;6(4):666-80.
2. Zhou Z, et al. J Neuroinflammation. 2017 Apr 5;14(1):75.
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