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MX107

Chemical Structure : MX107

CAS No.: 2170102-50-6

MX107 (MX 107)

Catalog No.: PC-35081Not For Human Use, Lab Use Only.

MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM.

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    Biological Activity

    MX107 is a novel potent survivin inhibitor, effectively suppresses MDA-MB-231 cells proliferation with IC50 of 3.1 uM.
    MX107 significantly enhances the tumoricidal efficacy of doxorubicin in TNBC cells.
    MX107 induces degradation of XIAP and/or cIAP1, which inhibited NF-κB activation by genotoxic agents.

    Physicochemical Properties

    M.Wt 376.5
    Formula C24H28N2O2
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    5-(((4-ethylbenzyl)oxy)methyl)-7-(pyrrolidin-1-ylmethyl)quinolin-8-ol

    References

    1. Wang W, et al. J Pharmacol Exp Ther. 2018 May 7. pii: jpet.118.249151.

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