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MYRA-A

Chemical Structure : MYRA-A

CAS No.: 3900-43-4

MYRA-A (NSC339585)

Catalog No.: PC-38694Not For Human Use, Lab Use Only.

MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

MYRA-A (NSC339585) is a small molecule Myc pathway response agent (MYRA) that inhibits Myc transactivation and interferes with the DNA-binding activity of Myc family proteins, with no effect on the E-box-binding protein USF.
MYRA-A (NSC339585) (3 uM) induces c-Myc-dependent apoptosis by MYRAs in Rat-1 cell lines, predominantly suppresses the growth of Myc overexpressing Tet-Myc cells.

Physicochemical Properties

M.Wt 340.379
Formula C19H20N2O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-((3-(dimethylamino)propyl)amino)-1,4-dihydroxyanthracene-9,10-dione

References

1. Hao Mo, et al. Proc Natl Acad Sci U S A. 2006 Apr 18;103(16):6344-9.

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