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Macamide B

Chemical Structure : Macamide B

CAS No.: 74058-71-2

Macamide B (N-Benzylpalmitamide, N-Benzylhexadecanamide)

Catalog No.: PC-28717Not For Human Use, Lab Use Only.

Macamide B is an effective active ingredient of maca, exerts a neuroprotective effect on neonatal hypoxic-ischemic brain damage (HIBD), enhances autophagy through the PI3K/AKT signaling pathway.

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Biological Activity

Macamide B is an effective active ingredient of maca, exerts a neuroprotective effect on neonatal hypoxic-ischemic brain damage (HIBD), enhances autophagy through the PI3K/AKT signaling pathway.
Macamide B pretreatment significantly decreases brain damage and improves the recovery of neural function after HIBD.
Macamide B pretreatment activates the PI3K/AKT signaling pathway after HIBD, enhances autophagy, and reduces hypoxic-ischemic (HI)-induced apoptosis.
Macamide B reduces HIBD-induced apoptosis and exerts neuroprotective effects on neonatal HIBD.
Macamide B suppresses lung cancer progression potentially via the ATM signaling pathway.

Physicochemical Properties

M.Wt 345.57
Formula C23H39NO
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-benzylpalmitamide

References

1. Yang X, et et al. Mol Neurobiol. 2022 May;59(5):2776-2798.

2. Tao H, et al. Oncol Lett. 2023 Feb 6;25(3):115.

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