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Chemical Structure : Mavatrep
CAS No.: 956274-94-5
Catalog No.: PC-45093Not For Human Use, Lab Use Only.
Mavatrep (JNJ-39439335) is a selective, high-affinity TRPV1 antagonist with IC50 of 4.6 nM (inhibition of capsaicin-induced Ca(2+) influx).
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $248 | In stock | |
| 25 mg | $398 | In stock | |
| 50 mg | $588 | In stock | |
| 100 mg | Get quote |
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Mavatrep (JNJ-39439335) is a selective, high-affinity TRPV1 antagonist with IC50 of 4.6 nM (inhibition of capsaicin-induced Ca(2+) influx).
Mavatrep (JNJ-39439335) exhibits potent in vitro functional activity and robust oral efficacy in multiple models of inflammatory pain.
| M.Wt | 422.4423 | |
| Formula | C25H21F3N2O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 28 mg/mL |
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| Chemical Name/SMILES |
Benzenemethanol, α,α-dimethyl-2-[2-[(1E)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazol-6-yl]- |
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1. Parsons WH, et al. J Med Chem. 2015 May 14;58(9):3859-74.
2. Mayorga AJ, et al. Scand J Pain. 2017 Aug 24;17:134-143.
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