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Chemical Structure : Mesendogen
CAS No.: 864716-85-8
Catalog No.: PC-38603Not For Human Use, Lab Use Only.
Mesendogen (Compound 6528694, MEG) is a small molecule inhibitor of TRPM6 channel, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells (hESCs) through alteration of magnesium homeostasis.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $148 | In stock | |
| 25 mg | $248 | In stock | |
| 50 mg | $428 | In stock | |
| 100 mg | Get quote |
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Mesendogen (Compound 6528694, MEG) is a small molecule inhibitor of TRPM6 channel, promotes mesoderm and definitive endoderm differentiation of human embryonic stem cells (hESCs) through alteration of magnesium homeostasis.
Mesendogen induces nearly homogeneous mesoderm differentiation in combination with the A-BVF condition, enhances mesoderm differentiation of hiPSCs and of variations of mesoderm induction conditions.
Mesendogen functions at the onset of mesendoderm differentiation but shows no effect on Nodal and Wnt signaling.
MEG functions by inhibiting cellular magnesium uptake.
| M.Wt | 400.844 | |
| Formula | C18H16ClF3N2OS | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
N-((2-chloro-5-(trifluoromethyl)phenyl)carbamothioyl)-4-isopropylbenzamide |
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1. Yijie Geng, et al. Heliyon. 2015 Dec 1;1(4):e00046.
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