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Methoxsalen

Chemical Structure : Methoxsalen

CAS No.: 298-81-7

Methoxsalen (8-Methoxypsoralen;Xanthotoxin;8-MOP)

Catalog No.: PC-45788Not For Human Use, Lab Use Only.

A potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

A potent tricyclic furocoumarin suicide that used to treat psoriasis, eczema, vitiligo and some cutaneous lymphomas in conjunction with exposing the skin to sunlight; inhibits human CYP2A6 and mouse CYP2A5, inhibits nicotine metabolism and alters the behavioral effects of nicotine in the mouse; also induces Ca2+ entry in MG63 human osteosarcoma cells.

Blood Cancer

Approved

Physicochemical Properties

M.Wt 216.1895
Formula C12H8O4
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

7H-Furo[3,2-g][1]benzopyran-7-one, 9-methoxy-

References

1. Lu YC, et al. Chin J Physiol. 2017 Jun 30;60(3):174-182.

2. Alsharari SD, et al. Nicotine Tob Res. 2014 Jan;16(1):18-25.

3. Bagdas D, et al. Neuropharmacology. 2014 Oct;85:67-72.

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