Catalog No.: PC-28058Not For Human Use, Lab Use Only.
Metyrapone (Su-4885, NSC-25265) is a potent and orally active 11β-hydroxylase (CYP11B1) inhibitor and autophagy activator, also inhibits the production of aldosterone, inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion in vivo.
Metyrapone (Su-4885, NSC-25265) is a potent and orally active 11β-hydroxylase (CYP11B1) inhibitor and autophagy activator, also inhibits the production of aldosterone, inhibits synthesis of endogenous adrenal corticosteroid, decreases glucocorticoid levels, and also affects behavior and emotion in vivo.
Physicochemical Properties
M.Wt
226.28
Formula
C14H14N2O
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
2-Methyl-1,2-di(pyridin-3-yl)propan-1-one
References
1. Roozendaal B, et al. Psychoneuroendocrinology. 1996 Nov;21(8):681-93.
