Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : Midkine inhibitor (iMDK)
CAS No.: 881970-80-5
Catalog No.: PC-61962Not For Human Use, Lab Use Only.
Midkine inhibitor (iMDK) is a small molecule inhibitor of the growth factor Midkine (MDK) that suppresses the endogenous expression of MDK but not other growth factors such as PTN or VEGF.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $248 | In stock | |
| 10 mg | $398 | In stock | |
| 25 mg | $588 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
Midkine inhibitor (iMDK) is a small molecule inhibitor of the growth factor Midkine (MDK) that suppresses the endogenous expression of MDK but not other growth factors such as PTN or VEGF.
Midkine inhibitor (iMDK) inhibits the cell growth of MDK-positive H441 lung adenocarcinoma cells that harbor an oncogenic KRAS mutation and H520 squamous cell lung cancer cells, inhibits PI3K pathway and induces apoptosis.
Midkine inhibitor (iMDK) significantly inhibits tumor growth in a xenograft mouse model in vivo.
| M.Wt | 376.4 | |
| Formula | C21H13FN2O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
3-[2-[(4-Fluorophenyl)methyl]imidazo[2,1-b]thiazol-6-yl]-2H-1-benzopyran-2-one |
|
1. Hao H, et al. PLoS One. 2013 Aug 16;8(8):e71093.
2. Ishida N, et al. Exp Cell Res. 2015 Jul 15;335(2):197-206.
3. Masui M, et al. Anticancer Res. 2016 Jun;36(6):2775-81.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
