Catalog No.: PC-23591Not For Human Use, Lab Use Only.
Miltefosine is a phosphatidylcholine analog with anti-leishmanial activity, inhibits PI3K/Akt activity, shows broad spectrum antimicrobial, anti-leishmanial and anticoronaviral activity.
Miltefosine is a phosphatidylcholine analog with anti-leishmanial activity, inhibits PI3K/Akt activity, shows broad spectrum antimicrobial, anti-leishmanial and anticoronaviral activity.
Miltefosine also is a CCR5 agonist that promotes MK differentiation and platelet production via MAPK and JAK2/STAT3 signaling.
Miltefosine is an antiprotozoal prescription medicine approved by the U.S. Food and Drug Administration (FDA) for the treatment of leishmaniasis.
Miltefosine shows broad spectrum antimicrobial, anti-leishmanial.
Miltefosine has a role as an antineoplastic agent, an antiprotozoal drug, an antifungal agent, an immunomodulator, an anti-inflammatory agent, an apoptosis inducer, a protein kinase inhibitor and an anticoronaviral agent.
Physicochemical Properties
M.Wt
407.58
Formula
C21H46NO4P
Appearance
Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility
10 mM in DMSO
Chemical Name/SMILES
Hexadecyl (2-(trimethylammonio)ethyl) phosphate
References
1. Uberall F, et al. Cancer Res. 1991 Feb 1;51(3):807-12.
2. Bhatt AP, et al. Blood. 2010 Jun 3;115(22):4455-63.
