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Chemical Structure : Mocravimod
Catalog No.: PC-60049Not For Human Use, Lab Use Only.
Mocravimod (KRP203) is a synthetic immunosuppressant that functions as a S1P1 receptor agonist.
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Mocravimod (KRP203) is a synthetic immunosuppressant that functions as a S1P1 receptor agonist.
Mocravimod (KRP203) significantly inhibits infiltration of inflammatory cells, expression of endothelin-1 and TGF-beta1, and IgG deposition and eventually attenuates neointimal formation and myocardial fibrosis.
Mocravimod (KRP203) prolongs graft survival and attenuates chronic rejection in rat skin and heart allografts.
| M.Wt | 443.986 | |
| Formula | C24H26ClNO3S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Shimizu H, et al. Circulation. 2005 Jan 18;111(2):222-9.
2. Takahashi M, et al. Transplant Proc. 2005 Jan-Feb;37(1):143-5.
3. Suzuki C, et al. J Heart Lung Transplant. 2006 Mar;25(3):302-9.
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