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Chemical Structure : Mpro inhibitor GD-9
Catalog No.: PC-49579Not For Human Use, Lab Use Only.
Mpro inhibitor GD-9 is a potent, covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.18 uM, exhibits antiviral potency against SARS-CoV-2 with EC50 of 2.64 uM.
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Mpro inhibitor GD-9 is a potent, covalent SARS-CoV-2 main protease (Mpro) inhibitor with IC50 of 0.18 uM, exhibits antiviral potency against SARS-CoV-2 with EC50 of 2.64 uM.
GD-9 shows similar antiviral potency to that of remdesivir (EC50 = 2.27 μM).
GD-9 presented favorable target selectivity for SARS-CoV-2 Mpro versus human cysteine proteases.
| M.Wt | 446.77 | |
| Formula | C18H18Cl3N3O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gao S, et al. J Med Chem. 2022 Dec 22;65(24):16902-16917.
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