MtbIMPDH inhibitor 31

Chemical Structure : MtbIMPDH inhibitor 31

Catalog No.: PC-28185Not For Human Use, Lab Use Only.

MtbIMPDH inhibitor 31 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, MtbIMPDH) with IC50 of 0.52 uM.

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Biological Activity

MtbIMPDH inhibitor 31 is a potent, specific inhibitor of Mycobacterium tuberculosis inosine 5'-monophosphate dehydrogenase (Mtb GuaB, MtbIMPDH) with IC50 of 0.52 uM.

Physicochemical Properties

M.Wt	466.34
Formula	C22H20BrN5O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	N-(4-(4-Bromophenyl)-1H-imidazol-2-yl)-2-(4-(1-methyl-1H-imidazol-4-yl)phenoxy)propanamide

References

1. Ana Trapero, et al. J Med Chem. 2018 Apr 12;61(7):2806-2822.

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