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N-aryl benzimidazole

Chemical Structure : N-aryl benzimidazole

CAS No.: 422554-26-5

N-aryl benzimidazole (NAB)

Catalog No.: PC-62315Not For Human Use, Lab Use Only.

N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells..

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

N-aryl benzimidazole (NAB) is a small molecule that strongly and selectively protects diverse cell types from α-syn toxicity, promotes endosomal transport events dependent on the E3 ubiquitin ligase Rsp5/Nedd4 in wild-type yeast cells.

Physicochemical Properties

M.Wt 375.856
Formula C22H18ClN3O
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

N-(2-chlorobenzyl)-1-(m-tolyl)-1H-benzo[d]imidazole-5-carboxamide

References

1. Tardiff DF, et al. Science. 2013 Nov 22;342(6161):979-83.

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