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N-phosphonacetyl-L-aspartate

Chemical Structure : N-phosphonacetyl-L-aspartate

CAS No.: 51321-79-0

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N-phosphonacetyl-L-aspartate (PALA, NSC 224131, Sparfosic acid)

Catalog No.: PC-20254Not For Human Use, Lab Use Only.

N-phosphonacetyl-L-aspartate (PALA, NSC 224131, Sparfosic acid) is a potent and reversible inhibitor of de novo pyrimidine biosynthesis, specifically inhibits aspartate transcarbamylase (ATCase).

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

N-phosphonacetyl-L-aspartate (PALA, NSC 224131, Sparfosic acid) is a potent and reversible inhibitor of de novo pyrimidine biosynthesis, specifically inhibits aspartate transcarbamylase (ATCase).

Physicochemical Properties

M.Wt 255.12
Formula C6H10NO8P
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO
Chemical Name/SMILES

N-(Phosphonoacetyl)-L-aspartic acid

References

1. Wadler S, et al. Eur J Cancer. 1996;32A(7):1254-1256.

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