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Chemical Structure : NAMI-A
Catalog No.: PC-45629Not For Human Use, Lab Use Only.
A ruthenium anticancer agent that has a selective effect on lung metastases of solid metastasizing tumors.
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NAMI-A is a ruthenium anticancer agent that has a selective effect on lung metastases of solid metastasizing tumors, inhibits the matrix metallo-proteinases MMP-2 and MMP-9 at micromolar concentrations.
NAMI-A significantly affects tumor cells with metastatic ability.
NAMI-A decreases the α5β1 integrin expression, and reduces FAK auto-phosphorylation on Tyr397 in HCT-116 colorectal cancer cells.
| M.Wt | 458.18 | |
| Formula | C5H10Cl4N2ORuS . C3H4N2 . H | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: 8.28 mg/mL |
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1. Pelillo C, et al. J Inorg Biochem. 2016 Jul;160:225-35.
2. Sava G, et al. Clin Cancer Res. 2003 May;9(5):1898-905.
3. Frausin F, et al. J Pharmacol Exp Ther. 2005 Apr;313(1):227-33.
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