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Chemical Structure : NBD-14270
Catalog No.: PC-72614Not For Human Use, Lab Use Only.
NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 180 nM.
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NBD-14270 (NBD14270) is an HIV-1 gp120 antagonist, shows antiviral activity against HIV-1HXB2 with IC50 of 89 nM.
NBD-14270 showed broad-spectrum antiviral activitiesa large panel of diverse HIV-1 Env-pseudotyped clinical isolates (mean IC50=0.18 uM), neutralized both the infant and maternal HIV-1 variants with mean IC50 of 0.37 uM.
| M.Wt | 425.43 | |
| Formula | C18H18F3N5O2S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Curreli F, et al. J Med Chem. 2020 Feb 27;63(4):1724-1749.
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