Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NBD-557
CAS No.: 333352-59-3
Catalog No.: PC-45974Not For Human Use, Lab Use Only.
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $384 | In stock | |
| 50 mg | $855 | In stock |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
A potent HIV-1 entry inhibitor that blocks the gp120-CD4 interaction; inhibits the fusion between HIV-1NL4-3-luc pseudotyped virus expressing HIV-1HXB2 (X4-tropic) envelope and U87-T4-CXCR4 cells with IC50 of 9.7 uM; inhibits the laboratory-adapted HIV-1 strains IIIB, MN, and V32 with IC50 of 5-16 uM.
HIV Infection
Preclinical
| M.Wt | 382.2953 | |
| Formula | C17H24BrN3O2 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Ethanediamide, N-(4-bromophenyl)-N'-(2,2,6,6-tetramethyl-4-piperidinyl)- (9CI) |
|
1. Zhao Q, et al. Virology. 2005 Sep 1;339(2):213-25.
2. Schön A, et al. Biochemistry. 2006 Sep 12;45(36):10973-80.
3. Curreli F, et al. Antimicrob Agents Chemother. 2014 Sep;58(9):5478-91.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
