NCC-149 (NCC149, NCC 149) | HDAC8 inhibitor

Chemical Structure : NCC-149

CAS No.: 1316652-41-1

NCC-149 (NCC 149, NCC149)

Catalog No.: PC-60134Not For Human Use, Lab Use Only.

NCC-149 (NCC149, NCC 149) is a potent and selective HDAC8 inhibitor with IC50 of 70 nM.

Packing	Price	Stock
5 mg	$198	In stock
10 mg	$328	In stock
25 mg	$528	In stock
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Biological Activity

NCC-149 (NCC149, NCC 149) is a potent and selective HDAC8 inhibitor with IC50 of 70 nM.
NCC-149 displays high selectivity over major HDACs (HDAC1: IC50 38 uM, HDAC2 >100 uM, HDAC4: IC50: 44 uM,HDAC6: IC50 2.4 uM).

Physicochemical Properties

M.Wt	326.374
Formula	C16H14N4O2S
Appearance	Solid
CAS No.
Storage	Solide Powder -20 °C 12 Months; 4°C 6 Months	In Solvent -80 °C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-hydroxy-3-(1-((phenylthio)methyl)-1H-1,2,3-triazol-4-yl)benzamide

References

1. Suzuki T, et al. ChemMedChem. 2014 Mar;9(3):657-64.

2. Suzuki T, et al. PLoS One. 2013 Jul 16;8(7):e68669.

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