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Chemical Structure : ND-336
Catalog No.: PC-70316Not For Human Use, Lab Use Only.
ND-336 (ND336) is a potent, selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively.
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ND-336 (ND336) is a potent, selective inhibitor of the gelatinases MMP2 and MMP9 and MMP13 with Ki of 85, 150 and 120 nM, respectively.
ND-336 has minimal effect on other MMPs.
ND-336 accelerates diabetic wound healing by lowering inflammation and by enhancing angiogenesis and re-epithelialization of the wound, thereby reversing the pathological condition.
| M.Wt | 371.9 | |
| Formula | C16H17NO3S2 • HCl | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Gao M, et al. Proc Natl Acad Sci U S A. 2015 Dec 8;112(49):15226-31.
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