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NDC-1171

Chemical Structure : NDC-1171

CAS No.: 892671-77-1

NDC-1171 (NDC1171)

Catalog No.: PC-26650Not For Human Use, Lab Use Only.

NDC-1171 is a potent, selective positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD).

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NDC-1171 is a potent, selective positive allosteric modulator/ activator of sarcoplasmic/endoplasmic reticulum calcium ATPase (SERCA) pump, improves SERCA-mediated Ca2+ cycling, attenuates cardiac functional decline in mouse model of Duchenne muscular dystrophy (DMD).

Physicochemical Properties

M.Wt 310.78
Formula C18H15ClN2O
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

3-chloro-4-methyl-N-(2-methylquinolin-8-yl)benzamide

References

1. Narra N, et al. bioRxiv [Preprint]. 2026 Mar 9:2026.03.05.709950.

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