NF023 | P2X1 antagonist | Probechem Biochemicals

Chemical Structure : NF023

CAS No.:

NF023 (NF023 hexasodium)

Catalog No.: PC-26164Not For Human Use, Lab Use Only.

NF023 hexasodium is a potent, selective and competitive P2X1 receptor (P2X1R) antagonist with IC50 of 0.21 uM (human P2X1), >100-fold selective over P2X3, P2X2, and P2X4 receptors.

Packing	Price	Stock
5 mg	$298	In stock
10 mg	$458	In stock
25 mg	$758	In stock
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Biological Activity

NF023 hexasodium is a potent, selective and competitive P2X1 receptor (P2X1R) antagonist with IC50 of 0.21 uM (human P2X1), >100-fold selective over P2X3, P2X2, and P2X4 receptors.

Physicochemical Properties

M.Wt	1162.85
Formula	C35H20N4Na6O21S6
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
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Solubility	10 mM in DMSO
Chemical Name/SMILES	sodium 8,8'-((3,3'-(carbonylbis(azanediyl))bis(benzoyl))bis(azanediyl))bis(naphthalene-1,3,5-trisulfonate)

References

1. F Soto, et al. Neuropharmacology. 1999 Jan;38(1):141-9.

2. M Freissmuth, et al. Mol Pharmacol. 1996 Apr;49(4):602-11.

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NF023 (NF023 hexasodium)

Biological Activity

Physicochemical Properties

References

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