Catalog No.: PC-22007Not For Human Use, Lab Use Only.
NMD670 (NMD-670) is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG).
NMD670 (NMD-670) is a potent, specific and orally bioavailable ClC-1 chloride channel inhibitor with EC50 of 1.6 uM, restores muscle function in rat models of myasthenia gravis (MG).
NMD670 shows no effect on Gm in a Cl− free experimental solution.
NMD670 (20 mg/kg) enhances neuromuscular transmission and restores muscle function in experimental autoimmune myasthenia gravis (MG) rats.
NMD670 (20 mg/kg) restores muscle force and motor performance in rat models of MG.
NMD670 improves running performance in a passive immunization MG rat model.
