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Chemical Structure : NS-638
CAS No.: 150493-34-8
Catalog No.: PC-42385Not For Human Use, Lab Use Only.
A nonpeptide calcium channel blocker that dose dependently inhibits AMPA-stimulated [3H]GABA-release from cultured cortical neurons with IC50 of 4.3 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 50 mg | $384 | In stock | |
| 100 mg | $520 | In stock |
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A nonpeptide calcium channel blocker that dose dependently inhibits AMPA-stimulated [3H]GABA-release from cultured cortical neurons with IC50 of 4.3 uM; blocks K(+)-stimulated intracellular Ca(2+)-elevation in cultured cerebellar granule cells with IC50 of 3.4 uM, reversibly blocks N- and L-type Ca(2+)-channels in cultured chick dorsal root ganglion cells (1-30 uM); exhibits anti-ischemic properties in vivo.
| M.Wt | 325.7161496 | |
| Formula | C15H11ClF3N3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
DMSO: ≥ 34 mg/mL |
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| Chemical Name/SMILES |
1H-Benzimidazol-2-amine, 1-[(4-chlorophenyl)methyl]-5-(trifluoromethyl)- |
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1. Møller A, et al. Neurol Res. 1995 Oct;17(5):353-60.
2. Olesen SP, et al. Acta Neurol Scand. 1997 Apr;95(4):219-24.
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