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Chemical Structure : NSC 23766 trihydrochloride
CAS No.: 1177865-17-6
Catalog No.: PC-44661Not For Human Use, Lab Use Only.
NSC 23766 trihydrochloride is a specific small molecule inhibitor of Rac GTPase.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $88 | In stock | |
| 25 mg | $138 | In stock | |
| 50 mg | $228 | In stock | |
| 100 mg | Get quote |
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NSC 23766 trihydrochloride is a specific small molecule inhibitor of Rac GTPase.
NSC 23766 trihydrochloride potently blockes serum or PDGF-induced Rac1 activation and lamellipodia formation without affecting the activity of endogenous Cdc42 or RhoA.
NSC 23766 trihydrochloride inhibits the proliferation, anchorage-independent growth and invasion phenotypes of human prostate cancer PC-3 cells.
| M.Wt | 530.9644 | |
| Formula | C24H38Cl3N7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
H2O: ≥ 32 mg/mL; DMSO: 7.6 mg/mL |
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| Chemical Name/SMILES |
4,6-Quinolinediamine, N6-[2-[[4-(diethylamino)-1-methylbutyl]amino]-6-methyl-4-pyrimidinyl]-2-methyl-, trihydrochloride |
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1. Gao Y, et al. Proc Natl Acad Sci U S A. 2004 May 18;101(20):7618-23.
2. Barros P, et al. Mol Cell Biol. 2009 Aug;29(15):4156-66.
3. Yoshida T, et al. Mol Cancer Ther. 2010 Jun;9(6):1657-68.
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