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Chemical Structure : NSC 311068
Catalog No.: PC-62521Not For Human Use, Lab Use Only.
NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
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NSC 311068 is a small molecule that directly tragets and inhibits STAT3/5, significantly and selectively suppresses the viability of AML cells with high level of TET1 expression both in vitro and in vivo.
NSC 311068 shows no inhibitory effect on the viability of TET1-low AML (i.e., NB4) cells.
| M.Wt | 278.242 | |
| Formula | C10H6N4O4S | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Jiang X, et al. Nat Commun. 2017 Dec 13;8(1):2099.
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