Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NSC 377071
CAS No.: 26097-80-3
Catalog No.: PC-60598Not For Human Use, Lab Use Only.
NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $118 | In stock | |
| 25 mg | $198 | In stock | |
| 50 mg | $298 | In stock | |
| 100 mg | Get quote |
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
NSC 377071 (NSC-377071, NSC377071, Cambendazole) is a novel ATG4B antagonist that inhibits autophagy, with no effect on mTOR and PI3K activities.
NSC 377071 directly inhibits cellular ATG4B activity induced by starvation or rapamycin and suppresses the lipidation of LC3B and autophagosome formation in response to starvation.
NSC 377071 suppresses Saos-2 osteosarcoma growth in vivo.
| M.Wt | 302.352 | |
| Formula | C14H14N4O2S | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Propan-2-yl N-[2-(1,3-thiazol-4-yl)-3H-benzimidazol-5-yl]carbamate |
|
1. Akin D, et al. Autophagy. 2014;10(11):2021-35.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
