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NSC 630668

Chemical Structure : NSC 630668

CAS No.: 330846-35-0

NSC 630668 (NSC630668)

Catalog No.: PC-62569Not For Human Use, Lab Use Only.

NSC 630668 is a Hsc70 inhibitor that inhibits the endogenous and DnaJ-stimulated ATPase activity of hsc70.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NSC 630668 is a Hsc70 inhibitor that inhibits the endogenous and DnaJ-stimulated ATPase activity of hsc70; blocks the hsc70-mediated translocation of a preprotein into yeast endoplasmic reticulum-derived microsomal vesicles.

Physicochemical Properties

M.Wt 822.8591
Formula C36H54N8O14
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

bis(6-(5-((ethoxycarbonyl)carbamoyl)-2,4-dioxo-3,4-dihydropyrimidin-1(2H)-yl)hexyl) hexane-1,6-diyldicarbamate

References

1. Fewell SW, et al. J Biol Chem. 2001 Jan 12;276(2):910-4.

2. Fewell SW, et al. J Biol Chem. 2004 Dec 3;279(49):51131-40.

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