Welcome to Shanghai Probechem Biochemicals Co Ltd !Global Supplier of Chemical Probes, Inhibitors & Agonists.
Chemical Structure : NT-0796
Catalog No.: PC-21283Not For Human Use, Lab Use Only.
NT-0796 is a potent, selective and brain-penetrant NLRP3 inflammasome inhibitor, inhibits IL-1β release from human PBMC cells with IC50 of 0.32 nM.
Bulk size, bulk discount!
E-mail: sales@probechem.com
Tech Support: tech@probechem.com
NT-0796 is a potent, selective and brain-penetrant NLRP3 inflammasome inhibitor, inhibits IL-1β release from human PBMC cells with IC50 of 0.32 nM.
NT-0796 is an isopropyl ester that undergoes intracellular conversion to NDT-19795.
NT-0796 is a potent and selective NLRP3 inflammasome inhibitor with demonstrated in vivo brain penetration.
NT-0796 shows no inhibition of IL-6 or TNFα from human PBMCs.
| M.Wt | 409.49 | |
| Formula | C23H27N3O4 | |
| Appearance | Solid | |
| Storage |
|
|
| Solubility |
10 mM in DMSO |
|
1. David Harrison, et al. J Med Chem. 2023 Oct 24. doi: 10.1021/acs.jmedchem.3c01398.
Copyright © 2022 probechem.com. All Rights Reserved. probechem Copyright
