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NTB-3119

Chemical Structure : NTB-3119

CAS No.: 2252473-48-4

NTB-3119 (NTB3119)

Catalog No.: PC-20080Not For Human Use, Lab Use Only.

NTB-3119 (NTB3119) is a novel benzothiopyranone derivative and anti-tuberculosis agent with potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains.

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Purity & Documentation Purity: >98% (HPLC)

Biological Activity

NTB-3119 (NTB3119) is a novel benzothiopyranone derivative and anti-tuberculosis agent with potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains.
NTB-3119 exhibited potent in vitro activity against both drug-susceptible and drug-resistant tuberculosis clinical strains.
NTB-3119 displayed potent in vivo efficacy with bactericidal activity in an acute mouse model of tuberculosis.

Physicochemical Properties

M.Wt 455.50
Formula C21H24F3N3O3S
Appearance Solid
CAS No.
Storage
Solide Powder
-20°C 12 Months; 4°C 6 Months
In Solvent
-80°C 6 Months; -20°C 6 Months
Shipping
Solubility

10 mM in DMSO

Chemical Name/SMILES

2-(4-(cyclohexylmethyl)piperazin-1-yl)-8-nitro-6-(trifluoromethyl)-4H-thiochromen-4-one

References

1. Xinbo Wang, et al. J Pharm Biomed Anal. 2023 Feb 5;224:115172.

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