NTRC-808 | NTSR2 agonist | Probechem Biochemicals

Chemical Structure : NTRC-808

NTRC-808 (NTRC808)

Catalog No.: PC-26997Not For Human Use, Lab Use Only.

NTRC-808 is a potent, selective nonpeptide partial agonist of GPCR neurotensin receptor type 2 (NTS2, NTSR2) with EC50 of 14 nM and Ki of 88 nM, is selective for NTS2 versus NTS1.

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Biological Activity

NTRC-808 is a potent, selective nonpeptide partial agonist of GPCR neurotensin receptor type 2 (NTS2, NTSR2) with EC50 of 14 nM and Ki of 88 nM, is selective for NTS2 versus NTS1.

Physicochemical Properties

M.Wt	457.91
Formula	C23H24ClN3O5
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	N-{[6-chloro-4-(2,6-dimethoxyphenyl)quinazolin-2-yl]carbonyl}-L-leucine

References

1. James B Thomas, et al. Bioorg Med Chem Lett. 2015 Jan 15;25(2):292-6.

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NTRC-808 (NTRC808)

Biological Activity

Physicochemical Properties

References

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