NU1025 | PARP inhibitor | Probechem Biochemicals

Chemical Structure : NU1025

CAS No.: 90417-38-2

NU1025 (NU-1025)

Catalog No.: PC-26674Not For Human Use, Lab Use Only.

NU1025 is a potent PARP inhibitor with IC50 of 400 nM and Ki of 48 nM, potentiates the cytotoxicity of ionizing radiation and anticancer agents, shows anti-cancer and neuroprotective activity.

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25 mg	$138	In stock
50 mg	$228	In stock
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Biological Activity

NU1025 is a potent PARP inhibitor with IC50 of 400 nM and Ki of 48 nM, potentiates the cytotoxicity of ionizing radiation and anticancer agents, shows anti-cancer and neuroprotective activity.

Physicochemical Properties

M.Wt	176.18
Formula	C9H8N2O2
Appearance	Solid
CAS No.
Storage	Solide Powder -20°C 12 Months; 4°C 6 Months	In Solvent -80°C 6 Months; -20°C 6 Months
Shipping
Solubility	10 mM in DMSO
Chemical Name/SMILES	8-Hydroxy-2-methylquinazolin-4(3H)-one

References

1. Boulton S, et al. Br J Cancer. 1995 Oct;72(4):849-56.

2. Bowman KJ, et al. Br J Cancer. 1998 Nov;78(10):1269-77.

3. Griffin RJ, et al. J Med Chem. 1998 Dec 17;41(26):5247-56.

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NU1025 (NU-1025)

Biological Activity

Physicochemical Properties

References

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