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Chemical Structure : NXL101
Catalog No.: PC-61939Not For Human Use, Lab Use Only.
NXL101 is a novel quinoline bacterial DNA gyrase and topoisomerase IV inhibitor that shows potent activity against gram-positive bacteria, including methicillin- and fluoroquinolone-resistant strains.
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NXL101 is a novel quinoline bacterial DNA gyrase and topoisomerase IV inhibitor that shows potent activity against gram-positive bacteria, including methicillin- and fluoroquinolone-resistant strains.
NXL101 inhibits S. aureus DNA gyrase and topoisomerase IV with IC50 of 1.0 and 18 uM, respectively.
| M.Wt | 504.635 | |
| Formula | C25H29FN2O4S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Black MT, et al. Antimicrob Agents Chemother. 2008 Sep;52(9):3339-49.
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