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Chemical Structure : NY0116
Catalog No.: PC-35773Not For Human Use, Lab Use Only.
NY0116 (NY 0116) is a small molecule neuromedin U receptor 2 (NMUR2) with EC50 of 27.76 uM for hNMUR1 and 13.61 uM for hNMUR2 in intracellular calcium mobilization assays.
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NY0116 (NY 0116) is a small molecule neuromedin U receptor 2 (NMUR2) with EC50 of 27.76 uM for hNMUR1 and 13.61 uM for hNMUR2 in intracellular calcium mobilization assays; decreases cAMP while stimulating calcium signaling in stably expressing NMUR2 HEK293 cells; significantly decreased high-fat diet consumption in vivo after acute administration, decreased body weight and more specifically, decreased the percentage of visceral adipose tissue (VAT) in obese mice after repeated administration.
| M.Wt | 345.446 | |
| Formula | C22H23N3O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Sampson CM, et al. Pharmacol Res Perspect. 2018 Aug 23;6(5):e00425.
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