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Nanchangmycin

Chemical Structure : Nanchangmycin

CAS No.: 65101-87-3

Nanchangmycin (Nanchangmycin A)

Catalog No.: PC-42189Not For Human Use, Lab Use Only.

A polyether ionophore antibiotic isolated from Streptomyces nanchangensis NS3226 that shows antibacterial and antiviral properties.

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Biological Activity

A polyether ionophore antibiotic isolated from Streptomyces nanchangensis NS3226 that shows antibacterial and antiviral properties; A potent inhibitor of Zika virus entry, also is active against other medically relevant viruses, including West Nile, dengue, and chikungunya viruses.

Physicochemical Properties

M.Wt 889.0956
Formula C47H77NaO14
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

DMSO: ≥ 26 mg/mL

Chemical Name/SMILES

6-Nonenoic acid, 8-[(2S,2'R,4'S,5R,5'S,7R,7'R,8R,9S,9'S,10'R)-9-hydroxy-2,4',8,10'-tetramethyl-2'-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-(hydroxymethyl)-3,5-dimethyl-2H-pyran-2-yl]-9'-[[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yl]oxy][2,7'-bi-1,

References

1. Liu T, et al. Chem Biol. 2008 May;15(5):449-58.

2. Liu T, et al. Chem Biol. 2006 Sep;13(9):945-55.

3. Rausch K, et al. Cell Rep. 2017 Jan 17;18(3):804-815.

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