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Chemical Structure : Negamycin
Catalog No.: PC-70301Not For Human Use, Lab Use Only.
A dipeptide antibiotic that inhibits the initiation of protein synthesis.
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A dipeptide antibiotic that inhibits the initiation of protein synthesis; also restores dystrophin expression in skeletal and cardiac muscles of the mdx mouse; interferes with decoding and translocation by simultaneous interaction with rRNA and tRNA.
| M.Wt | 248.283 | |
| Formula | C9H20N4O4 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Arakawa M, et al. J Biochem. 2003 Nov;134(5):751-8.
2. Polikanov YS, et al. Mol Cell. 2014 Nov 20;56(4):541-50.
3. Cocozaki AI, et al. Proc Natl Acad Sci U S A. 2016 Jul 19;113(29):8188-93.
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