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Chemical Structure : Nesuparib
CAS No.: 2055357-64-5
Catalog No.: PC-73432Not For Human Use, Lab Use Only.
Nesuparib (JPI-547, NOV140201) is a potent, oral, dual inhibitor of PARP 1/2 and Tankyrase 1/2, demonstrates anti-tumor activity in BRCA-deficient cancer.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $198 | In stock | |
| 10 mg | $298 | In stock | |
| 25 mg | $488 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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Nesuparib (JPI-547, NOV140201) is a potent, oral, dual inhibitor of PARP 1/2 and Tankyrase 1/2, demonstrates anti-tumor activity in BRCA-deficient cancer.
Nesuparib (JPI-547, NOV140201) shows anti-tumor activity in BRCA-deficient xenograft models as a single-agent and in combination with chemotherapy and immune checkpoint inhibitors.
| M.Wt | 400.486 | |
| Formula | C23H24N6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-Pyridinecarbonitrile, 6-[4-[(1,2,3,4,5,6-hexahydro-5-oxobenzo[h]-1,6-naphthyridin-8-yl)methyl]-1-piperazinyl]- |
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1. Seock-Ah Im, et al. 2021 ASCO Annual Meeting I.
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