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Nesvacumab

Chemical Structure : Nesvacumab

CAS No.:

Nesvacumab (Anti-human Ang-2 mAb, human IgG1-Kappa; REGN910)

Catalog No.: PC-Ab1101Not For Human Use, Lab Use Only.

Nesvacumab (REGN910) is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand vascular growth factor called angiopoietin2 (Ang2) with high affinity (Kd=24 pM), but shows no binding to Ang1..

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

Biological Activity

Nesvacumab (REGN910) is a fully human immunoglobulin G1 (IgG1) monoclonal antibody that specifically binds and inactivates the Tie2 receptor ligand vascular growth factor called angiopoietin2 (Ang2) with high affinity (Kd=24 pM), but shows no binding to Ang1.

Physicochemical Properties

M.Wt
Formula Human IgG1-Kappa
Appearance Solid
CAS No.
Storage
Solide Powder
-20 °C 12 Months; 4°C 6 Months
In Solvent
-80 °C 6 Months; -20°C 6 Months
Shipping
Solubility

PBS, pH 7.0 Contains no stabilizers or preservatives

Chemical Name/SMILES

References

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