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Chemical Structure : Nonivamide
CAS No.: 2444-46-4
Catalog No.: PC-45355Not For Human Use, Lab Use Only.
Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 200 mg | $78 | In stock | |
| 500 mg | $118 | In stock | |
| 1 g | Get quote |
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Nonivamide is a capsaicin analog that acts as an agonist of TRPV1 channel.
Nonivamide causes calcium release from the ER and alters the transcription of GADD153, GADD45alpha, GRP78/BiP, ATF3, CCND1, and CCNG2 in human bronchial epithelial and alveolar cells.
Nonivamide stimulates the Ca(2+)-dependent release of serotonin and dopamine in SH-SY5Y cells at 1 uM.
Nonivamide also enhances miRNA let-7d expression and decreases adipogenesis PPARγ expression in 3T3-L1 cells.
| M.Wt | 293.4012 | |
| Formula | C17H27NO3 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
|
| Chemical Name/SMILES |
Nonanamide, N-[(4-hydroxy-3-methoxyphenyl)methyl]- |
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1. Rohm B, et al. Mol Nutr Food Res. 2013 Nov;57(11):2008-18.
2. Thomas KC, et al. J Pharmacol Exp Ther. 2007 Jun;321(3):830-8.
3. Rohm B, et al. J Cell Biochem. 2015 Jun;116(6):1153-63.
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