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Chemical Structure : Nrf2 activator 16
Catalog No.: PC-62795Not For Human Use, Lab Use Only.
Nrf2 activator 16 is a potent Keap1-Nrf2 and Keap1-p-p62 protein-protein interaction inhibitor with IC50 of 0.91 uM and 1.8 uM respectively.
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Nrf2 activator 16 is a potent Keap1-Nrf2 and Keap1-p-p62 protein-protein interaction inhibitor with IC50 of 0.91 uM and 1.8 uM respectively.
Nrf2 activator 16 upregulates Nrf2 response genes measured by a luciferase cell reporter assay.
| M.Wt | 498.568 | |
| Formula | C24H22N2O6S2 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Saito T, et al. Nat Commun. 2016 Jun 27;7:12030.
2. Yasuda D, et al. Bioorg Med Chem Lett. 2016 Dec 15;26(24):5956-5959.
3. Marcotte D, et al. Bioorg Med Chem. 2013 Jul 15;21(14):4011-9.
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