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Chemical Structure : OAT-2068
CAS No.: 2221950-65-6
Catalog No.: PC-62539Not For Human Use, Lab Use Only.
OAT-2068 is a potent, selective, orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1) with IC50 of 29 nM, 143-fold selectivity over mAMCase.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 5 mg | $358 | In stock | |
| 10 mg | $548 | In stock | |
| 25 mg | Get quote | ||
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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OAT-2068 is a potent, selective, orally bioavailable inhibitor of mouse chitotriosidase (mCHIT1) with IC50 of 29 nM, 143-fold selectivity over mAMCase.
OAT-2068 exhibits excellent pharmacokinetic profile and is an ideal and unique tool for studying the role of CHIT1 in biological models.
| M.Wt | 446.04 | |
| Formula | C23H36ClN7 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
3-(4-((2S,5S)-2-(4-chlorobenzyl)-4-isobutyl-5-methylpiperazin-1-yl)piperidin-1-yl)-1H-1,2,4-triazol-5-amine |
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1. Mazur M, et al. Bioorg Med Chem Lett. 2017 Dec 22. pii: S0960-894X(17)31221-0.
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