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Chemical Structure : OAT-870
Catalog No.: PC-21913Not For Human Use, Lab Use Only.
OAT-870 is a potent dual AMCase and CHIT1 inhibitor with IC50 of 48/74 nM (human/ mouse CHIT1) and 22/30 nM (h/mAMCase).
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OAT-870 is a potent dual AMCase and CHIT1 inhibitor with IC50 of 48/74 nM (human/ mouse CHIT1) and 22/30 nM (h/mAMCase).
OAT-870 displays good in vitro activity for both human and murine chitinases.
OAT-870 exhibits significant anti-inflammatory effect in HDM-induced airway inflammation model in mice.
| M.Wt | 376.89 | |
| Formula | C18H25ClN6O | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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1. Marzena Mazur, et al. Int J Mol Sci. 2021 Jul; 22(13): 6966.
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