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Chemical Structure : ONO-7300243
CAS No.: 638132-34-0
Catalog No.: PC-42284Not For Human Use, Lab Use Only.
ONO7300243 is a novel potent, selective, orally available lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 uM.
| Packing | Price | Stock | Quantity |
|---|---|---|---|
| 10 mg | $128 | In stock | |
| 25 mg | $218 | In stock | |
| 50 mg | Get quote | ||
| 100 mg | Get quote |
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ONO7300243 is a novel potent, selective, orally available lysophosphatidic acid receptor 1 (LPA1) antagonist with IC50 of 0.16 uM.
ONO7300243 exhibits good selectivity (>50-fold) toward LPA1over LPA2; shows good efficacy in vivo, reduces intraurethral pressure in rats without affecting the blood pressure (30mg/kg. p.o.).
| M.Wt | 461.54944 | |
| Formula | C28H31NO5 | |
| Appearance | Solid | |
| Storage |
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| Solubility |
10 mM in DMSO |
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| Chemical Name/SMILES |
Benzeneacetic acid, 4-[[(3,5-dimethoxy-4-methylbenzoyl)(3-phenylpropyl)amino]methyl]- |
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1. Terakado M, et al. ACS Med Chem Lett. 2016 Aug 19;7(10):913-918.
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