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ONO-9780307

Chemical Structure : ONO-9780307

CAS No.: 856691-44-6

ONO-9780307 (ONO9780307)

Catalog No.: PC-62670Not For Human Use, Lab Use Only.

ONO-9780307 is a potent, specific lysophosphatidic acid receptor 1 (LPA1) inhibitor with IC50 of 27 nM.

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Purity & Documentation Purity: >98% (HPLC) Select Batch:

    Biological Activity

    ONO-9780307 is a potent, specific lysophosphatidic acid receptor 1 (LPA1) inhibitor with IC50 of 27 nM.
    ONO-9780307 exhibits specific binding to LPA1 with pKd of 8.00 (9.9 nM).

    Physicochemical Properties

    M.Wt 521.61
    Formula C30H35NO7
    Appearance Solid
    CAS No.
    Storage
    Solide Powder
    -20 °C 12 Months; 4°C 6 Months
    In Solvent
    -80 °C 6 Months; -20°C 6 Months
    Shipping
    Solubility

    10 mM in DMSO

    Chemical Name/SMILES

    1-[(2S,3S)-2-[(2,3-Dihydro-1H-inden-2-yl)methyl]-3-(3,5-dimethoxy-4-methylphenyl)-3-hydroxypropyl]-4-(methoxycarbonyl)-1H-pyrrole-3-acetic acid

    References

    1. Chrencik JE, et al. Cell. 2015 Jun 18;161(7):1633-43.

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